Glutaric anhydride is used in the production of glutaric acid family pharmaceuticals. A glutaric acid ester as carrier system for sustained delivery of lamuvidine (3TC) dimers. NSC 16640. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. Get medical attention. It does not represent a new labelling, classification or hazard statement, neither reflect other factors that affect the susceptibility of the effects described, such as duration of exposure or substance concentration (e.g. glutaric anhydride . Its derivatives are also used in certain corrosion inhibitors, some surfactants and metal finishing compounds. China Glutaric Anhydride manufacturers - Select 2021 high quality Glutaric Anhydride products in best price from certified Chinese Anhydride manufacturers, Acid Anhydride suppliers, wholesalers and factory on Made-in-China.com Mol. Causes skin irritation. Pharmaceutics 2015, 12 (7), 2505-2516. Substances which have been registered and can be placed on the EEA market by those companies with a valid registration. BPR regulation aims to improve the functioning of the biocidal products market in the EU, while ensuring a high level of protection for humans and the environment. IF IN EYES: Rinse cautiously with water for several minutes. The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA). More information about the EC Inventory can be found here. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.) The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data. Union List of Authorized Substances: Annex I, Plastics Food Contact Regulation 10/2011/EU, as amended by Regulation 2020/1245/EU, 3 September 2020, Registration, Evaluation, Authorisation and Restriction of Chemicals, Chemical Agents Directive and Carcinogens or Mutagens Directive, Plastic Materials and Articles Regulation, EC Inventory, FCM and Articles Regulation, Annex I - Authorised Substances, Other, FCM and Articles Regulation, Annex I - Authorised Substances, Pre-Registration process, FCM and Articles Regulation, Annex I - Authorised Substances, 5-[(4-carboxybutanoyl)oxy]-5-oxopentanoic acid, EC Inventory, C&L Inventory, Registration dossier, Pre-Registration process, Other, FCM and Articles Regulation, Annex I - Authorised Substances, Substances of very high concern identification, Recommendation for the Authorisation List, Getting started with EU chemicals legislation, Classification of substances and mixtures, Harmonised classification and labelling (CLH). … Glutaric acid anhydride . Moisture sensitive. UNII-63OFI15S80. This section provides an overview of the calculated volume at which the substance is manufactured or imported to the European Economic Area (EU28 + Iceland, Liechtenstein and Norway). Welcome to the ECHA website. Title Journal or Book Year; Conformation of non-aromatic ring compounds −91. PubChem Substance ID 24895139. The Support section provides tools and practical guidance to companies which have responsibilities under the EU chemicals legislation. ECHA has no public registered data on the types of manufacture using this substance. The Prior Informed Consent Regulation administers the import and export of certain hazardous chemicals and places obligations on companies who wish to export these chemicals to non-EU countries. …atoms, behaves similarly to yield glutaric anhydride. SALES SPECIFICATION Our site saves small pieces of text information (cookies) on your device in order to deliver better content and for statistical purposes. Glutaric anhydride for synthesis. Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. Substances indicated, in 2009, as being intended to be registered by at least one company in the EEA. REACH regulation aims to improve the protection of human health and the environment from the risks that can be posed by chemicals. Search results for L Glutamic Acid at Sigma-Aldrich. 3 Temperatures as high as 200 °C have Anhydrid kyseliny glutarove [Czech] EINECS 203-593-6. Search results for glutamic anhydride at Sigma-Aldrich. Remove contact lenses, if present and easy to do. Molecular Formula C 5 H 6 O 3; Average mass 114.099 Da; Monoisotopic mass 114.031693 Da; ChemSpider ID 7652 MDL number MFCD00006679. Please note: Precautionary measures and guidance on safe use concern the use and handling of the specific substance as such, not of the presence of the substance in other articles or mixtures. Glutaric anhydride 108-55-4 95 4. With the increase of glutaric anhydride content, the total heat released during the curing reaction and the glass transition temperature (Tg) increased. Compre una gran selección de productos Lactones y obtenga más información sobre Glutaric anhydride, 98%, Alfa Aesar™: Lactones Organoheterocyclic compounds . Guidance on safe use - recommendations by substance registrant on the proper use of the substance in various situations. 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. Information on precautionary measures and the safe use is submitted by the registrant of a substance and the registrant is solely responsible for its accuracy and completeness. The ‘Hazard classification and labelling’ section shows the hazards of a substance based on the standardised system of statements and pictograms established under the CLP (Classification Labelling and Packaging) Regulation. This information is only displayed if the substance is well–defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. US4874824A US07/123,683 US12368387A US4874824A US 4874824 A US4874824 A US 4874824A US 12368387 A US12368387 A US 12368387A US 4874824 A US4874824 A US 4874824A Authority US United States Prior art keywords polymer the products in which the substance may be used) may refer to uses as intermediate and under controlled conditions, for which there is no consumer exposure. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. It has a role as a human metabolite and a Daphnia magna metabolite. ECHA organises consultations to get feedback from all interested parties and to gather the widest possible range of scientific information for the regulatory processes. The per substance REACH registration status is being calculated and will be made available as soon as possible. Immediately call a POISON CENTER or doctor/physician. © Copyright 2021 Alfa Aesar, Thermo Fisher Scientific. H302-H312-H315-H318. The CLP Regulation ensures that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union through classification and labelling of chemicals. | Lazrek HB, Vasseur JJ, Secrist J 3rd, Engels JW Nucleosides Nucleotides Nucleic Acids 2007;26(8-9):1103-6. doi: 10.1080/15257770701519452. When information is available in all sources, the first two are displayed as a priority. For readability purpose, only non-confidential use descriptors occurring in more than 5% of total occurrences are displayed. The information is aggregated from the data coming from REACH substance registrations provided by industry. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. The source of the information is mentioned in the introductory sentence of the hazard statements. Additional applications such as the production of polymers, corrosion inhibitors, surfactants and metal finishing compounds might be available. If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9. NSC16640 Glutaric acid is naturally produced in the body during the metabolism of some amino acids, including lysine and tryptophan. Glutaric acid is an alpha,omega-dicarboxylic acid that is a linear five- carbon dicarboxylic acid. 2H-Pyran-2,6(3H)-dione, dihydro-Pentanedioic acid anhydride. The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. Their decomposition at temperatures above 300°C and a heating time as long as 6 h generates CO 2 and condensation products. All Rights Reserved. Release to the environment of this substance can occur from industrial use: as an intermediate step in further manufacturing of another substance (use of intermediates). 2 This is a very old and commercially useful process. Crystallization of glutaric anhydride in the presence of β-cyclodextrin (βCD) from aqueous solution resulted in crystals of the glutaric acid/βCD inclusion complex. Other relevant information includes the following: To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory. This substance has an industrial use resulting in manufacture of another substance (use of intermediates). With the dehydrating agent, such asacetic anhydride, heating the glutaric acid to dehydrate it and obtain glutaric anhydride(108-55-4). These notifications can be provided by manufacturers, importers and downstream users. *Please select more than one item to compare ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. This information is only displayed if the substance is well-defined, its identity is not claimed confidential and there is sufficient information available in ECHA’s databases for ECHA’s algorithms to generate a molecular structure. The molecular structure is based on structures generated from information available in ECHA’s databases. Defects in this metabolic pathway can lead to a disorder called glutaric aciduria, where toxic byproducts build up and can cause severe encephalopathy. The use information is displayed per substance life cycle stage (consumer use, in articles, by professional workers (widespread uses), in formulation or re-packing, at industrial sites or in manufacturing). Tel: 1-800-343-7276 or 1-978-521-6405 Póngase en contacto con todos los distribuidores / fabricantes de Glutaric anhydride que se indican a continuación y pregunte por los precios, las normas de los envases y las posibilidades de transporte. For a detailed overview on identified uses and environmental releases, please consult the registered substance factsheet. Expired - … Production Use only outdoors or in a well-ventilated area. Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. Note that for readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed. - Find MSDS or SDS, a COA, data sheets and more information. Precautionary statements - describe recommended measures to minimise or prevent adverse effects resulting from exposure to a hazardous product or improper storage or handling of a hazardous product. If generated, an InChI string will also be generated and made available for searching. This section is based on three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). Glutaric anhydride is used in the production of glutaric acid family pharmaceuticals. Substances listed in the EINECS, ELINCS, or NLP inventories. Dispose of contents/ container to an approved waste disposal plant, Catalog Sales & Customer Service Take off contaminated clothing and wash before reuse. InfoCards are updated when new information is available. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance and no text is automatically generated for the InfoCard. Other . It is also used in improvement of electrode/electrolyte interfaces in High-Voltage Spinel Lithium-Ion batteries as an electrolyte additive. IF INHALED: Remove to fresh air and keep at rest in a position comfortable for breathing. REACH registered substance data was upgraded on 9th November. The described Product category (i.e. Glutaric anhydride . (M-F, 8AM-7PM EST) The result was verified by NMR spectroscopic experiments, which moreover showed that βCD … BRN 0110051. dihydro-3H-pyran-2,6-dione. We apologise for the inconvenience in the meantime. email: specialquotes@alfa.com, Technical Service The Waste Framework Directive aims to protect the environment and human health from the generation and management of waste and to improve efficient use of resources. Tel: 1-800-343-0660 or 1-978-521-6300 Carboxylic acids donate hydrogen ions if a base is present to accept them. This information has not been reviewed or verified by ECHA, and may change without prior notice. Glutaric acid A = 1144 . Pyroglutaric acid. Danger! ECHA has no public registered data indicating whether or into which articles the substance might have been processed. According to the classification provided by companies to ECHA in REACH registrations this substance is harmful if swallowed, causes serious eye damage and causes skin irritation. Some substance identifiers may have been claimed confidential, or may not have been provided, and therefore not be displayed. Substances may have impurities and additives that lead to different classifications. This is the first paper that reports the combination of glutaric anhydride and adipic acid as curing agents for epoxidized plant oils to produce thermosets ranging from flexible to hard. They react in this way with all bases, both organic (for example, the amines) and inorganic. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. email: tech@alfa.com. ECHA has no public registered data indicating whether or in which chemical products the substance might be used. the electronic edition of the Official Journal of the European Union. Glutaric acid may be employed as starting reagent in the synthesis of glutaric anhydride. ECHA has no public registered data on the routes by which this substance is most likely to be released to the environment. The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. Chen, H.; Liu, C.; Chen, D.; Madrid, K.; Peng, S.; Dong, X.; Zhang, M.; Gu, Y. Bacteria-Targeting Conjugates Based on Antimicrobial Peptide for Bacteria Diagnosis and Therapy. This substance has not been registered under the REACH Regulation, therefore as yet ECHA has not received any data about this substance from registration dossiers. It is used as a raw material in the manufacture of flavours. disodium tetraborate EC no. Glutaric anhydride EC Number: 203-593-6 EC Name: Glutaric anhydride CAS Number: 108-55-4 Molecular formula: C5H6O3 IUPAC Name: 5-[(4-carboxybutanoyl)oxy]-5-oxopentanoic acid The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH). inside a watch) or with very low concentrations considered not to pose risks to human health or the environment. The ‘Substance identity’ section is calculated from substance identification information from all ECHA databases. The examples provided are generic examples and may not apply to the specific substance you are viewing. This section provides links to the list of precautions (precautionary statements) and to the guidance on safe use, if they have been provided in REACH registration dossiers. 80% adipic acid. Substances for which classification and labelling data have been notified to ECHA by manufacturers or importers. Clear. If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. Hazard Statements: Fax: 1-978-521-6350 For breathing electrode/electrolyte interfaces in High-Voltage Spinel Lithium-Ion batteries as an electrolyte additive publications, e.g )... Measures on fire-fighting, transport and recycling and disposal substances for which classification and labelling, and may not complete... This way with all bases, alcohols and amines chemicals Agency ( ECHA ), data sheets more! Obtain glutaric anhydride in the following categories: Moisture Sensitive which articles the substance manufacturers and importers consult... Ether, dimethyl sulfoxide and methanol and water manufacturers or importers Find all of the substance might been. For which classification and labelling data have been registered and can be found here the EINECS, ELINCS or. Two are displayed as a raw material in the European chemicals Agency ( ECHA ) valid... Some mono- and di-alkyl substituted glutaric anhydrides Succinic acid anhydride la información necesaria y especificaciones. The ‘ substance identity ’ section is calculated from substance identification information from all ECHA databases with. Support section provides tools and practical guidance to companies which have been notified ECHA... Five- carbon dicarboxylic acid structure is based on the types of manufacture using this substance is most to! To be released to the CLP Regulation - recommendations by substance registrant the! Registrations provided by industry the databases of the European Union specific hazard Statements some substances can provided. 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Toxic byproducts build up and can cause severe encephalopathy Alfa Aesar, Thermo Fisher scientific data sheets and information!
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